{"id":23884,"date":"2026-03-12T16:09:38","date_gmt":"2026-03-12T15:09:38","guid":{"rendered":"https:\/\/2biol.com\/?p=23884"},"modified":"2026-03-12T16:13:07","modified_gmt":"2026-03-12T15:13:07","slug":"sonde-gavage-orale-roditori","status":"publish","type":"post","link":"https:\/\/2biol.com\/en\/sonde-gavage-orale-roditori\/","title":{"rendered":"Flexible Probes for Oral Gavage | FTP Guide and Choice"},"content":{"rendered":"<h1 data-section-id=\"m7wxy1\" data-start=\"343\" data-end=\"425\">Flexible oral gavage probes in rodents: guide to selection and use<\/h1>\n<p data-start=\"427\" data-end=\"754\"><strong data-start=\"430\" data-end=\"492\">Flexible oral gavage probes (FTP: plastic feeding tubes)<\/strong> are now an increasingly popular solution for <strong data-start=\"552\" data-end=\"606\">oral administration of compounds in mice and rats.<\/strong> Compared with traditional rigid stainless steel probes, they offer several advantages in terms of <strong data-start=\"704\" data-end=\"753\">safety, ease of use and animal welfare.<\/strong> <\/p>\n<p data-start=\"756\" data-end=\"902\">In this guide we look at what they are, how to choose the correct size, and some best practices for use in <strong data-start=\"872\" data-end=\"901\">rodent oral dosing<\/strong>.<\/p>\n<hr data-start=\"904\" data-end=\"907\">\n<h1 data-section-id=\"1gw4odf\" data-start=\"909\" data-end=\"951\">What are FTPs<\/h1>\n<p data-start=\"953\" data-end=\"1093\">The <span style=\"color: #0000ff;\"><a style=\"color: #0000ff;\" href=\"https:\/\/2biol.com\/prodotti\/instech-ftp\/\"><strong>FTPs<\/strong><strong data-start=\"956\" data-end=\"981\">(plastic feeding tubes)<\/strong><\/a><\/span> are probes made of <strong data-start=\"1007\" data-end=\"1033\">medical polypropylene<\/strong>, the same material used for many disposable syringes.<\/p>\n<p data-start=\"1095\" data-end=\"1112\">They consist of:<\/p>\n<ul data-start=\"1114\" data-end=\"1340\">\n<li data-section-id=\"2t6976\" data-start=\"1114\" data-end=\"1186\">\n<p data-start=\"1116\" data-end=\"1186\">A <strong data-start=\"1119\" data-end=\"1151\">Luer lock or slip fit<\/strong> for connection to the syringe<\/p>\n<\/li>\n<li data-section-id=\"3jd5xw\" data-start=\"1187\" data-end=\"1257\">\n<p data-start=\"1189\" data-end=\"1257\">A <strong data-start=\"1192\" data-end=\"1211\">hose<\/strong> available in different lengths and diameters<\/p>\n<\/li>\n<li data-section-id=\"1hv9126\" data-start=\"1258\" data-end=\"1340\">\n<p data-start=\"1260\" data-end=\"1340\">A <strong data-start=\"1264\" data-end=\"1293\">soft rounded tip<\/strong> designed to reduce the risk of injury.<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"1342\" data-end=\"1485\">Unlike traditional metal probes, these probes are <strong data-start=\"1410\" data-end=\"1421\">disposable<\/strong>, so they do not require washing or autoclaving.<\/p>\n<hr data-start=\"1487\" data-end=\"1490\">\n<h1 data-section-id=\"9s7kah\" data-start=\"1492\" data-end=\"1556\">Why use plastic probes instead of steel probes<\/h1>\n<p data-start=\"1558\" data-end=\"1687\">More and more laboratories are switching from metal probes to <strong data-start=\"1624\" data-end=\"1655\">flexible gavage probes<\/strong>, mainly for three reasons:<\/p>\n<p data-start=\"1689\" data-end=\"1825\"><strong data-start=\"1689\" data-end=\"1725\">Increased safety for the animal<\/strong><br data-start=\"1725\" data-end=\"1728\">The soft tip reduces the risk of accidental insertion into the trachea during the procedure.<\/p>\n<p data-start=\"1827\" data-end=\"1935\"><strong data-start=\"1827\" data-end=\"1863\">Lower risk of contamination<\/strong><br data-start=\"1863\" data-end=\"1866\">Being disposable, they eliminate the need for cleaning and sterilization.<\/p>\n<p data-start=\"1937\" data-end=\"2073\"><strong data-start=\"1937\" data-end=\"1968\">Improved operational management<\/strong><br data-start=\"1968\" data-end=\"1971\">They simplify daily work in laboratories and reduce the risk of contamination between samples.<\/p>\n<p data-start=\"2075\" data-end=\"2255\"><a href=\"https:\/\/www.instechlabs.com\/blog\/significantly-more-esophageal-inflammation-found-in-mice-dosed-with-metal-gavage-tubes-than-plastic\"><span style=\"color: #0000ff;\"><strong>Recent studies<\/strong><\/span><\/a> also indicate that the use of flexible probes represents an <strong data-start=\"2156\" data-end=\"2222\">improvement in animal welfare practices (refinement)<\/strong> in oral gavage procedures.<\/p>\n<hr data-start=\"2257\" data-end=\"2260\">\n<h1 data-section-id=\"26ake8\" data-start=\"2262\" data-end=\"2313\">How to choose the correct probe size<\/h1>\n<p data-start=\"2315\" data-end=\"2363\">The choice of probe depends mainly on:<\/p>\n<ul data-start=\"2365\" data-end=\"2467\">\n<li data-section-id=\"jm1t16\" data-start=\"2365\" data-end=\"2388\">\n<p data-start=\"2367\" data-end=\"2388\"><strong data-start=\"2367\" data-end=\"2388\">weight of the animal<\/strong><\/p>\n<\/li>\n<li data-section-id=\"hg8wf4\" data-start=\"2389\" data-end=\"2437\">\n<p data-start=\"2391\" data-end=\"2437\"><strong data-start=\"2391\" data-end=\"2437\">viscosity of the solution to be administered<\/strong><\/p>\n<\/li>\n<li data-section-id=\"19zmcj8\" data-start=\"2438\" data-end=\"2467\">\n<p data-start=\"2440\" data-end=\"2467\"><strong data-start=\"2440\" data-end=\"2466\">length of the esophagus<\/strong>.<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"2469\" data-end=\"2606\">There is no such thing as a universal size: it is often useful to <strong data-start=\"2522\" data-end=\"2545\">test multiple options<\/strong> to find the one best suited to your application.<\/p>\n<hr data-start=\"2608\" data-end=\"2611\">\n<h2 data-section-id=\"1nygkj2\" data-start=\"2613\" data-end=\"2637\">Probe length<\/h2>\n<p data-start=\"2639\" data-end=\"2747\">The ideal length is approximately the <strong data-start=\"2696\" data-end=\"2746\">distance between the animal&#8217;s mouth and sternum<\/strong>.<\/p>\n<p data-start=\"2749\" data-end=\"2812\">Using the correct length helps reduce the risk of:<\/p>\n<ul data-start=\"2814\" data-end=\"2876\">\n<li data-section-id=\"wszgkp\" data-start=\"2814\" data-end=\"2843\">\n<p data-start=\"2816\" data-end=\"2843\"><strong data-start=\"2816\" data-end=\"2843\">liquid aspiration<\/strong><\/p>\n<\/li>\n<li data-section-id=\"zptf5u\" data-start=\"2844\" data-end=\"2876\">\n<p data-start=\"2846\" data-end=\"2876\"><strong data-start=\"2846\" data-end=\"2875\">perforation of the esophagus<\/strong>.<\/p>\n<\/li>\n<\/ul>\n<hr data-start=\"2878\" data-end=\"2881\">\n<h2 data-section-id=\"vojw9k\" data-start=\"2883\" data-end=\"2902\">Gauge (diameter)<\/h2>\n<p data-start=\"2904\" data-end=\"2958\">The <strong data-start=\"2907\" data-end=\"2928\">probe gauge<\/strong> should be chosen according to:<\/p>\n<ul data-start=\"2960\" data-end=\"3013\">\n<li data-section-id=\"xy8mu8\" data-start=\"2960\" data-end=\"2987\">\n<p data-start=\"2962\" data-end=\"2987\">size of rodent<\/p>\n<\/li>\n<li data-section-id=\"j8pmb\" data-start=\"2988\" data-end=\"3013\">\n<p data-start=\"2990\" data-end=\"3013\">viscosity of the compound.<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"3015\" data-end=\"3083\">More viscous solutions generally require <strong data-start=\"3061\" data-end=\"3082\">larger diameters<\/strong>.<\/p>\n<hr data-start=\"3085\" data-end=\"3088\">\n<h1 data-section-id=\"1rzfmyq\" data-start=\"3090\" data-end=\"3117\">Most commonly used dimensions<\/h1>\n<p data-start=\"3119\" data-end=\"3184\">Below are some general directions used in the workshops.<\/p>\n<h3 data-section-id=\"ynr3hg\" data-start=\"3186\" data-end=\"3194\">Mice<\/h3>\n<ul data-start=\"3196\" data-end=\"3308\">\n<li data-section-id=\"xlsory\" data-start=\"3196\" data-end=\"3221\">\n<p data-start=\"3198\" data-end=\"3221\"> <strong data-start=\"3198\" data-end=\"3209\">&lt; 20 g:<\/strong> FTP-22-25<\/p>\n<\/li>\n<li data-section-id=\"1tu35jg\" data-start=\"3222\" data-end=\"3260\">\n<p data-start=\"3224\" data-end=\"3260\"><strong data-start=\"3224\" data-end=\"3236\">20-30 g:<\/strong> FTP-20-30 \/ FTP-20-34<\/p>\n<\/li>\n<li data-section-id=\"i447uw\" data-start=\"3261\" data-end=\"3308\">\n<p data-start=\"3263\" data-end=\"3308\"> <strong data-start=\"3263\" data-end=\"3274\">&gt; 30 g:<\/strong> FTP-20-38 (most common size)<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"3310\" data-end=\"3400\">For particularly viscous solutions, a <strong data-start=\"3375\" data-end=\"3399\">polyurethane probe<\/strong> may be preferable.<\/p>\n<h3 data-section-id=\"78epfg\" data-start=\"3402\" data-end=\"3411\">Rats<\/h3>\n<ul data-start=\"3413\" data-end=\"3584\">\n<li data-section-id=\"1fpv6gm\" data-start=\"3413\" data-end=\"3451\">\n<p data-start=\"3415\" data-end=\"3451\"> <strong data-start=\"3415\" data-end=\"3427\">&lt; 100 g:<\/strong> FTP-18-30 \/ FTP-22-38<\/p>\n<\/li>\n<li data-section-id=\"192ez44\" data-start=\"3452\" data-end=\"3492\">\n<p data-start=\"3454\" data-end=\"3492\"><strong data-start=\"3454\" data-end=\"3468\">100-200 g:<\/strong> FTP-18-38 \/ FTP-18-50<\/p>\n<\/li>\n<li data-section-id=\"9yzqgw\" data-start=\"3493\" data-end=\"3546\">\n<p data-start=\"3495\" data-end=\"3546\"><strong data-start=\"3495\" data-end=\"3509\">200-300 g:<\/strong> FTP-18-75 or polyurethane models<\/p>\n<\/li>\n<li data-section-id=\"l29nop\" data-start=\"3547\" data-end=\"3584\">\n<p data-start=\"3549\" data-end=\"3584\"> <strong data-start=\"3549\" data-end=\"3561\">&gt; 300 g:<\/strong> FTP-15-78 \/ FTP-15-100<\/p>\n<\/li>\n<\/ul>\n<p data-section-id=\"ai5gt1\" data-start=\"3591\" data-end=\"3631\"><span style=\"color: #0000ff;\"><strong><a style=\"color: #0000ff;\" href=\"https:\/\/2biol.com\/wp-content\/uploads\/2024\/05\/2B-Instech-brochure-FTP.pdf\">HERE<\/a> <\/strong><\/span>the complete brochure.<\/p>\n<hr>\n<h1 data-section-id=\"ai5gt1\" data-start=\"3591\" data-end=\"3631\">Immobilization of the animal (scruff)<\/h1>\n<p data-start=\"3633\" data-end=\"3744\"><strong data-start=\"3637\" data-end=\"3666\">Proper immobilization<\/strong> is essential to safely perform <strong data-start=\"3711\" data-end=\"3743\">oral gavage in mice and rats<\/strong>.<\/p>\n<p data-start=\"3746\" data-end=\"3858\">Before the procedure, it is advisable to <strong data-start=\"3784\" data-end=\"3827\">accustom the animals to handling in<\/strong> order to reduce stress.<\/p>\n<h3 data-section-id=\"ynr3hg\" data-start=\"3860\" data-end=\"3868\">Mice<\/h3>\n<p data-start=\"3870\" data-end=\"4050\">The rat is grasped gently at the base of the tail and then <strong data-start=\"3947\" data-end=\"3991\">clamped by the neck skin (scruff)<\/strong> between thumb and forefinger, keeping it upright.<\/p>\n<h3 data-section-id=\"78epfg\" data-start=\"4052\" data-end=\"4061\">Rats<\/h3>\n<p data-start=\"4063\" data-end=\"4211\">The rat is grabbed by the <strong data-start=\"4095\" data-end=\"4114\">skin of the neck<\/strong> and lifted while keeping the body upright, preventing it from prying with its hind legs.<\/p>\n<hr data-start=\"4213\" data-end=\"4216\">\n<h1 data-section-id=\"18tj4uy\" data-start=\"4218\" data-end=\"4243\">Oral gavage technique<\/h1>\n<p data-start=\"4245\" data-end=\"4279\">After immobilizing the animal:<\/p>\n<ol data-start=\"4281\" data-end=\"4502\">\n<li data-section-id=\"16wpqbz\" data-start=\"4281\" data-end=\"4373\">\n<p data-start=\"4284\" data-end=\"4373\">Insert the probe <strong data-start=\"4302\" data-end=\"4359\">slightly to the right or left of the midline of<\/strong> the mouth<\/p>\n<\/li>\n<li data-section-id=\"ujrokj\" data-start=\"4374\" data-end=\"4410\">\n<p data-start=\"4377\" data-end=\"4410\">advance the probe without forcing<\/p>\n<\/li>\n<li data-section-id=\"fyqseu\" data-start=\"4411\" data-end=\"4456\">\n<p data-start=\"4414\" data-end=\"4456\">administer the contents of the syringe<\/p>\n<\/li>\n<li data-section-id=\"g3mqy\" data-start=\"4457\" data-end=\"4502\">\n<p data-start=\"4460\" data-end=\"4502\">Remove the probe and monitor the animal.<\/p>\n<\/li>\n<\/ol>\n<p data-start=\"4504\" data-end=\"4668\"><strong data-start=\"4526\" data-end=\"4561\">There should be no resistance<\/strong> during insertion. If resistance appears or <strong data-start=\"4598\" data-end=\"4625\">liquid<\/strong> is observed <strong data-start=\"4598\" data-end=\"4625\">coming out of the nose<\/strong>, stop the procedure immediately. <\/p>\n<p data-start=\"4504\" data-end=\"4668\"><span style=\"color: #0000ff;\"><strong><a style=\"color: #0000ff;\" href=\"https:\/\/www.instechlabs.com\/mouse-oral-gavage-watch\">Mouse Oral Gavage Training VIDEO.<\/a><\/strong><\/span><\/p>\n<p><span style=\"color: #0000ff;\"><strong><a style=\"color: #0000ff;\" href=\"https:\/\/www.instechlabs.com\/rat-oral-gavage-watch\">Rat Oral Gavage Training VIDEO.<\/a><\/strong><\/span><\/p>\n<hr>\n<p data-start=\"4882\" data-end=\"5053\"><a href=\"2biol@2biol.com\"><span style=\"color: #0000ff;\"><strong>Write to us<\/strong> <\/span><\/a>for more information.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Flexible oral gavage probes in rodents: guide to selection and use Flexible oral gavage probes (FTP: plastic feeding tubes) are now an increasingly popular solution for oral administration of compounds in mice and rats. Compared with traditional rigid stainless steel probes, they offer several advantages in terms of safety, ease of use and animal welfare. [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":23882,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2766,2764],"tags":[],"class_list":["post-23884","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-animals","category-pre-clinical-en"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.6 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Flexible Probes for Oral Gavage | FTP Guide and Choice - 2B<\/title>\n<meta name=\"description\" content=\"Disposable oral gavage tubes for mice and rats: advantages, recommended sizes, and techniques of use for dosing studies in rodents.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/2biol.com\/en\/sonde-gavage-orale-roditori\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Flexible Probes for Oral Gavage | FTP Guide and Choice - 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